Malaria P.f/P.v Rapid Test Kit
Malaria is one of the world most prevalent parasitic diseases and ranks third in the world major infectious diseases in terms of mortality. The protozoal parasites that cause malaria are from the Plasmodium genus.
When using this Malaria Rapid Test, it is important to know that four species of Plasmodium protozoa cause malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae and Plasmodium ovale.
Transmitted principally by the Anopheles mosquito, malaria infections may also occur from contacting infected blood, such as from blood transfusions.
P. falciparum accounts for the majority of infections and is the most lethal. P. vivax, P. malariae and P. orale cause a less severe form of malaria with intermittent fever which is usually neither debilitating nor fatal. Severe anemia is often attributed to the cause of death from a malaria infection.
It is intended to aid in the rapid diagnosis of human malaria infections and to aid in the differential diagnosis of Plasmodium falciparum (P.f.) infections from P. vivax (P.v.) infections.
This Malaria P.f/P.v Rapid Test Kit is a rapid test for the qualitative detection of Malaria Antigen P.f or/and P.v in human venous and capillary whole blood.
This Malaria Antigen P.f/P.v Test is based on the principle of sandwich immunoassay for detection of Malaria Antigen P.f and P.v Monoclonal antibodies are employed to identify Malaria Antigen specifically. The histidine-rich protein II (HRPII) monoclonal antibody (T1 Line), P.v specific pLDH monoclonal antibody (T2 Line) and IgG polyclonal antibody (Control Line)
are used as the solid of the assay. The monoclonal antibody can bind with the Malaria Antigen P.f or/and P.v in the whole blood specimen. During the test procedures, the Malaria Antigen P.f in the whole blood specimen will bind with the colloidal gold- HRPII monoclonal antibody specifically, or/and the Malaria Antigen P.v will bind with the colloidal gold- pLDH monoclonal antibody specifically. Because of capillary and chromatographic effects of the Nitrocellulose membrane, the complexes migrate along the membrane to the antibody line (T1,T2), form Abα-Ag-Abβ-Au complexes and remain captured in the T line. As a result a red colored band develops in T1 or/and/T2 and the result is positive. If there is no Malaria Antigen in the whole blood specimen, there is no red band in the Test zone, indicating negative result. No matter if there’s Malaria Antigen P.f/P.v in the whole blood specimen, when the complexes migrate along the Control zone, a red band must be developed in the C zone To serve as a procedure control, a colored line will appear at the Control Region (C), of each strip, if the test has been performed properly.
【STORAGE AND STABILITY】
The kit should be stored at 2-30°C on the sealed pouch.
The test must remain in the sealed pouch until use.
Do not use if there is evidence of microbial contamination or precipitation. Biological contamination of dispensing equipment, containers or reagents can lead to false results.